In 2015 a Facebook post claimed that Bravecto chewable flea and tick remedy is fatal to dogs. A family who had adopted a dog from Pet Helpers asserted that the dog had died as a result of being given Bravecto chewables and that another of their dogs had also nearly died.

However, studies at the time suggested that Bravecto was safe. But that's not the end of the story. Following thousands of adverse reaction reports, Bravecto remains a potential cause for concern.

As the warning spread on social media during 2015, it was picked up by the website Snopes, who attempt to confirm or quash various 'rumours'.

Investigating the claim, Snopes quoted a 2014 study published in the Parasites & Vectors journal where 32 beagles were treated with Bravecto (fluralaner) and no serious adverse side effects were attributed to the medication.

The full study can be found here.

Wilson Street Veterinary. Dr. Michael Mogavero stated that the drug had been extensively tested prior to its release and had proved safe for dogs - click here.

Snopes concluded that the Bravecto rumours were 'unproven'.

The family of the dog asserted that one of their pets had died within a day of being given Bravecto chewables and that another of their dogs had nearly died after being given the same treatment at the same time. The update also asserted that Bravecto chewables were responsible for the dog's death and that several other dogs had died of liver and kidney failure shortly after taking the same medication.

As of August 2018 - The European Medicines Agency (EMA) reports that there were 8,692 adverse reactions after the administration of Bravecto. And there were 2,056 reported deaths.

The US Food and Drug Administration (FDA) issued a warning on September 20, 2018 about the isoxazoline flea and tick products fluralaner for dogs and cats (Bravecto®), afoxalaner for dogs (Nexgard®), and saroloner for dogs (Simparica®). The recently introduced isoxazoline, lotilaner (Credelio®) for dogs falls into this same class.

Dogs and cats with no known prior medical history of muscle tremors, ataxia, and seizures have experienced those adverse reactions to this class of flea and tick preventive pesticides.

Side effects including excessive thirst, dehydration, nausea, panting and pink colored skin. There's also the MDR1 mutation which has also been found in Shetland Sheepdogs (Shelties), Rough Collies, Australian Shepherds, Old English Sheepdogs, English Shepherds, German Shepherds, Long-haired Whippets, Silken Windhounds, and a variety of mixed breed dogs.

The MDR1 gene mutation undergoes one or more mutations that allow a higher absorption of drugs and toxic substances to enter the central nervous system and then they can breach the blood-brain barrier and create adverse reactions. This is very serious when you're considering flea and tick medication for these breeds. 

With all this mind, some pet owners don't believe that Bravecto chews are worth the risk.

If your pet experiences a bad reaction from any spot-on product, immediately bath with mild soap, rinse with large amounts of water, and call your veterinarian.


This information is not meant to be a substitute for veterinary care. Always follow the advice provided by your veterinarian.